If you have a history of severe allergic reaction after a previous dose of any hepatitis B vaccine, or to any ingredient of HEPLISAV‑B, including yeast, do not take HEPLISAV‑B.
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Healthy or not, unvaccinated people can contract hepatitis B. For most people, hepatitis B clears on its own. For those who don't clear the virus, the resulting health complications—including cirrhosis and liver cancer—can be lifelong or even deadly. Because there is no way of knowing for sure who will clear the virus and who will not, prevention with vaccination is critical to help ensure protection. HEPLISAV‑B may not work for everyone. Not all liver cancer is caused by hepatitis B.
Beginning in 1991, hepatitis B vaccination became the standard of care for infants as part of a routine childhood vaccination series, making it the first shot your baby likely received before leaving the hospital. If you were born before 1991, you may not be protected against hepatitis B.
The CDC recommends hepatitis B vaccination for all adults aged 19-59, adults 60 years or older with risk factors, and adults 60 or older without known risk factors. This recommendation applies to adults who have not received a complete hepatitis B vaccine series in their lifetime.
Your vaccination records should tell you, but if you can't find them, you should discuss it with your healthcare provider.
HEPLISAV‑B is the first and only adult hepatitis B vaccine that offers protection with only 2 doses in 1 month. Other adult hepatitis B vaccines require at least 3 doses and take 6 months to complete. Series completion is critical to help ensure protection.
HEPLISAV‑B is approved by the FDA and was studied in clinical trials of more than 10,000 patients. The most common side effects include pain at the injection site, tiredness, and headache.
You are encouraged to report vaccine adverse events to the US Department of Health and Human Services. Visit www.vaers.hhs.gov to file a report, or call 1-800-822-7967.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-332-1088.
95.7% of adults were protected after completing both doses of HEPLISAV‑B in clinical trials. Hepatitis B vaccines have demonstrated long-term protection.
Most insurance plans cover HEPLISAV‑B. Ask your doctor or pharmacist about vaccination coverage and reimbursement to learn more.
HBV infection cannot result from use of HEPLISAV‑B. Talk to your doctor or find a pharmacist to learn more.
The CDC recommends hepatitis B vaccination for all adults aged 19-59 and for adults aged ≥60 years with risk factors. Adults aged ≥60 years without risk factors may receive hepatitis B vaccination. This recommendation applies to adults who have not received a complete hepatitis B vaccine series in their lifetime.
HEPLISAV‑B is a vaccine to prevent hepatitis B. It does not treat an infection of hepatitis B. Talk to your doctor or find a pharmacist to learn more.
You may experience mild soreness, redness, or swelling at the injection site. Please read the full Prescribing Information for details on potential reactions, and be sure to contact your doctor with any concerns.
You can typically get vaccinated at your pharmacy or doctor's office. Use our pharmacy finder to find a convenient location near you. Once you find one, don’t forget your insurance card and a valid ID.
Depending on your pharmacy, you can schedule your second dose when you get your first, or you can just walk in.
Be sure to complete 2 doses of HEPLISAV‑B in order to be protected. If you forget to get your second dose of HEPLISAV‑B, talk to your healthcare provider or pharmacist.
CDC=Centers for Disease Control and Prevention; FDA=Food and Drug Administration; HBV=hepatitis B virus
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HEPLISAV‑B is a shot given to adults 18 years of age and older to help prevent infection caused by the hepatitis B virus.
HEPLISAV‑B is usually given in the arm muscle. HEPLISAV‑B is given in 2 doses, 1 month apart, by a healthcare provider.
IMPORTANT SAFETY INFORMATION
If you have a history of severe allergic reaction after a previous dose of any hepatitis B vaccine, or to any ingredient of HEPLISAV‑B, including yeast, do not take HEPLISAV‑B.
HEPLISAV‑B must be given by a medical professional, who will monitor you afterwards, to check for allergic reaction.
If you are immunocompromised, or receiving immunosuppressant therapy, you may have less of an immune response to HEPLISAV‑B.
Some people have hepatitis B infection without being aware of it or showing any symptoms. If you already have hepatitis B present in your body, HEPLISAV‑B may not prevent hepatitis B infection.
The most common side effects include pain at the injection site, tiredness, and headache.
HEPLISAV‑B was not studied in pregnant or nursing women. Tell your provider if you are pregnant or plan to become pregnant or are breast feeding.
Vaccination with HEPLISAV‑B may not protect all individuals.
Talk to your healthcare provider to determine if HEPLISAV‑B is right for you.
ADDITIONAL IMPORTANT INFORMATION
HEPLISAV‑B does not treat liver diseases such as cirrhosis or liver cancer.
Not all liver cancer is caused by the hepatitis B virus.
